Synthesis Ofsome Benzothiazole Derivatives and Kinetic Studies of Their Oxidation Using Chloramine-T in Acid Medium
نویسندگان
چکیده
منابع مشابه
Oxidation of mephenesin and guaifenesin with chloramine-B in hydrochloric acid medium: Design of kinetic model
Kinetics of oxidation of mephenesin and guaifenesin by sodium N-chlorobenzenesulfonamide (CAB) have been investigated in HCl medium at 303 K. The oxidation behaviour is similar for both the substrates. The rate shows a first order dependence on both [CAB]0 and [HCl], and is fractional in [substrate]0. The orders individually in [H ] and [Cl] are fractional. The variation of ionic strength and a...
متن کاملOxidation of tricyclic antidepressant drugs with chloramine-T in acidic solutions: kinetic, mechanistic and thermodynamic studies
The kinetics of the oxidation of two tricyclic antidepressants (TCA) namely, imipramine (IMP) and clomipramine (CLM) with sodium N-chloro-p-toluenesulfonamide or chloramine-T (CAT) in HClO4 medium was studied at 300 K. The two reactions followed identical kinetics with a first-order dependence of rate on [CAT]o and fractional order dependence on [TCA]o. The reaction is catalyzed by H(+) ions wi...
متن کاملKinetics and Mechanistic Study of Oxidation of Amoxicillin by Chloramine-t in Acid Medium
This spectroscopic study presents the kinetics and degradation pathways of oxidation of amoxicillin (AMOX) by chloramines-T (CAT) in acidic medium at a constant ionic strength of 0.105 mol dm-3 at 298 K. Reaction between AMOX and CAT in acidic medium exhibits 1:1 stoichiometry (AMOX:CAT). The reaction is of a first-order in both [CAT] and [AMOX]. The order with respect to acid concentration was...
متن کاملSynthesis, Computational Studies and Anticonvulsant Activity of Novel Benzothiazole Coupled Sulfonamide Derivatives
We report herein the synthesis of ¾ substituted benzene sulfonamides linked via phenyl ring to a benzothiazole moiety. The title compounds in the two series namely N-(4-(benzothiazole-2-yl) phenyl) 4- substituted benzene sulfonamides and N-(4-(benzothiazole-2-yl) phenyl) 3- substituted benzene sulfonamides were synthesized by condensing 2-(3/4-aminophenyl) benzothiazole with various...
متن کاملPd(II) catalysis in oxidation of D-ribose and arabinose by chloramine-T in acidic medium: A kinetic study
Kinetic investigations on Pd(II) catalyzed oxidation of D-ribose and D-arabinose by acidic solution of chloramine-T in the presence of mercuric acetate, as a scavenger have been made in the temperature range of 30°-45°C. The rate shows first order kinetics in case of chloramine-T and order of reaction is zero and one with respect to substrate and Pd(II) respectively. Increase in [Cl] showed pos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IOSR Journal of Applied Chemistry
سال: 2017
ISSN: 2278-5736,2278-5736
DOI: 10.9790/5736-1006020107